mouse, n. /maʊs/
In the sense of the computer input device, named for its two primary functions. The creator of the mouse – Douglas Engelbart of the Stanford Research Institute – designed it to ease movement and selection of onscreen objects and text. The resulting acronym (from movement and selection) of “movse” was inconvenient to pronounce, so the v character was treated as a Latin u.
This is why the correct plural is “computer mouses,” not “computer mice.”